
Metagenomic Sequencing
Our Metagenomic Sequencing at the Weill Cornell Medicine Microbiome Core provides comprehensive insights into microbial community composition and function. By employing advanced technologies, we enable researchers to explore the vast biodiversity of microbial ecosystems, paving the way for significant scientific discoveries.
Efficient Extraction and Library Preparation
We utilize the Promega Max Prep and Promega Maxwell RSC 48 Instrument to extract DNA from various samples. The extraction ensures high-quality, intact genomic DNA for subsequent Metagenomic Sequencing analysis.
Following extraction, we will generate metagenomic libraries using the Illumina Nextera XT Preparation Kit. Our highly efficient Shotgun Metagenomic Sequencing process enables the construction of ready-to-sequence libraries with minimal hands-on time.


High-Throughput Multiplexing
We provide multiplexing capabilities of up to 384 samples per Metagenomic Sequencing run. This high throughput maximizes resource efficiency while reducing project turnaround times.
This scalability is particularly beneficial for large-scale operations or collaborative studies, enabling researchers to gather extensive data promptly.
Advanced Sequencing Technology
Once the library pool is ready, it will be sequenced as Paired-End (PE) 150-reads on the cutting-edge Illumina NovaSeq X.
Using Illumina advanced sequencing technology, the high-quality data decodes the complete microbial diversity found in samples, including valuable information on functional genes and metabolic pathways.

Additional Services
-
What types of samples do you accept?We accept diverse human, mouse, environmental & clinical samples for 16S rRNA Sequencing.
-
How much does 16S Sequencing cost?Cornell customers pay $100/sample for 16s sequencing services, while other customers pay $110/sample. Pricing per sample decreases with larger volume orders, and each project is unique. Please view our pricing page and contact us for more information.
-
How long does the sequencing process take?A 16S Sequencing project typically takes around 4 weeks from when we physically receive samples. Please contact us to discuss your project and get an accurate timeline estimate.
-
What data delivery options do you provide?16S rRNA Sequencing analysis results are provided anywhere in the world via PubShare.